原著論文

2017/09/01

【A02・入鹿山班】Essential structure of orexin 1 receptor antagonist YNT-707, Part Role of the 4,5-epoxy ring for binding with orexin 1 receptor.

Essential structure of orexin 1 receptor antagonist YNT-707, Part Role of the 4,5-epoxy ring for binding with orexin 1 receptor.

Yamamoto N, Ohrui S, Okada T, Yata M, Saitoh T, Kutsumura N, Nagumo Y, Irukayama-Tomobe Y, Ogawa Y, Ishikawa Y, Watanabe Y, Hayakawa D, Gouda H, Yanagisawa M, Nagase H.

Bioorg Med Chem Lett. 2017 Sep 1 27 (17) : 4176-4179. Doi:10.1016/j.bmcl.2017.07011. Epub 2017 Jul 4.